[Technology Frontier] University Professor Reveals High-pressure Homogenizer: How Is This Technology Reshaping Multiple Industries From Nanomedicines to Plant-based Milk?
Recently, Caspeter (Hangzhou) Nanotechnology Co., Ltd. and Professor Ye from Wenzhou University of Technology were interviewed by a TV station, deeply analyzing how the high-pressure homogenizer, this “hidden champion”, has become a revolutionary tool in the fields of food, pharmaceuticals, cosmetics, etc. through breakthroughs in core technologies.
Core technology: The “Golden Combination” of ultra-high pressure and micro-jet
Professor Ye pointed out that the core of the high-pressure homogenizer lies in the synergistic effect of ultra-high pressure microjet technology and the interactive homogenization chamber:
Ultra-high pressure physical effect: The material is pressurized to 2700bar by a plunger pump, forming a high-speed jet in the micro-jet cavity. By taking advantage of shear, cavitation and collision effects, the particles are refined to the nanometer level (minimum below 85nm). Intelligent pressure control and energy-saving design: Utilizing single-phase pressure-increasing technology, the pressure stability reaches ±0.5MPa, while reducing energy consumption. Desktop devices (such as the PT-20 model) strike a balance between laboratory precision and industrial-grade performance.
Professor Li, based on practical cases, revealed the multi-field value of high-pressure homogenizers:
Food industry: Dairy products: The diameter of fat globules in milk is refined to less than 1μm, resulting in a smoother texture, improved stability, and an extended shelf life.
In the pharmaceutical field: Nanomedicines and anti-tumor drugs (such as paclitaxel) are homogenized to form 50-200nm particles, increasing solubility by 3-5 times and enhancing targeting. Vaccine production: Influenza vaccines adopt nano-emulsion technology. After homogenization, the particle size is uniform, and the immune effect is enhanced.
Cosmetics and materials: Ceramide nanocaterals increase transdermal absorption efficiency by three times and extend the shelf life of creams and ointments to 18 months.
Nanomaterials: Carbon nanotubes and graphene are uniformly dispersed in polymers, enhancing the performance of composite materials.
Professor Ye disclosed that the team is developing a fusion system of continuous flow homogenization technology and microfluidics, aiming to keep the error rate of liposome preparation within 5% and explore the application of mRNA vaccine encapsulation in gene therapy. He emphasized: “The high-pressure homogenizer has been upgraded from a single device to a core platform of nanotechnology and will drive in-depth innovation in fields such as biomanumanufacturing and environmental protection materials in the future.”
Post time: Jul-10-2025